Vaera: Chapter 6
"But they hearkened not to Moses for anguish of spirit"

Rabbi Yehuda says "anguish of spirit" means the people did not have enough rest or enough breath. But Rabbi Shimon answers that it means two things, that Binah had not yet released joy, and so rest and freedom were not yet available; and that Malchut had not yet ruled in the world to institute just laws.