There are many methods by which Scripture conveys obscure allusions. Rabbi Yitzchak offers the example of the title verse in conjunction with "But the wicked are like the troubled sea." This, we learn, contains an indication that the seed of Esau would destroy one of the two Temples. Rabbi Aba then expounds on Jacob's eventual victory over Esau. His success was granted by the world above, without whose permission no power can be exerted in the physical realm.
Our egos perpetrate the illusion that we are in full control of our lives, when in reality we are subject to dark forces created by our own self-involved behavior. This deception keeps us ignorant of the Negative Inclination, and of the spiritual tools that can eradicate it. Only the Light of The Creator can enlighten and strengthen us in the struggle to overthrow our dark side. Alone, we remain convinced that we are captains of our fate, until chaos strikes and leaves us stunned, vulnerable, and broken. The Light of this passage internalizes these spiritual truths, deepening our connection to the mystical power of the Zohar, and drawing Divine assistance from worlds on high.